These SARS-CoV-2 variants pose an ongoing threat to human society. As of December 2021, the World Health Organization (WHO) has defined five variants of concern (VOCs)-Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), Delta (B.1.617.2 and AY lineages) and Omicron (originally B.1.1.529, then reclassified into BA lineages)-as well as two variants of interest, Lambda (C.37) and Mu (B.1.621) 4. Newly emerging SARS-CoV-2 variants need to be carefully monitored for potentially increased transmissibility, pathogenicity and resistance to vaccine-induced immunity and antiviral drugs. Nature volume 603, pages 700–705 ( 2022) Cite this article The Genotype to Phenotype Japan (G2P-Japan) Consortium,. Attenuated fusogenicity and pathogenicity of SARS-CoV-2 Omicron variant
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